Cool. "B. dentium's genome also reveals why it is so hard to get rid of. It sports a number of genes that increase their expression in acid environments, which probably help it survive in dental cavities, where acid destroys tooth enamel. B. dentium may even have evolved to protect itself against dental hygiene: When Ventura and his colleagues grew the bug in a variety of mouthwashes and antiseptics, they found that it ramped up the activity of several genes, including those for proteins that bind up toxic compounds and render them harmless."