PLoS Genetics: A Broad Brush, Global Overview of Bacterial Sexuality

“These results have several implications. Firstly, plasmids and ICEs share the same protein families, and should be considered as alternative vehicles for conjugation pathways, rather than as distinct entities. Secondly, the potential for horizontal gene transfer and homologous recombination is widespread throughout microbes, which can help explain why mobile genetic elements are so common in their genomes. Finally, conjugative elements provide a ubiquitous mechanism for the facile transmission of genes between discrete clades, whose predominance has not previously been adequately appreciated.”

The facility with which microbes tinker with DNA within and between species has always fascinated me. Indeed, my current interest is in horizontal gene transfer.

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