This paper is trying to measure and model the effectiveness of multi-drug antimicrobial chemotherapy.
Antibiotics are notorious for losing effectiveness as the target microbe gains resistance to that single antibiotic. Being able to treat microorganism with multiple drugs is sometimes the only way to manage the disease – as in HIV or TB.
But to be able to create better multi-drug cocktails, we’ll need to better model the contributions of each component.
This paper seeks to show how to measure and prove the effectiveness of the component sin a two-drug system. But I am wondering how we’ll do the same for more than two drugs (HIV anti-viral therapy has at least three components).
