Big Data, healthcare, devices, and quantified self
When I was at SXSW, I spent most of my time at either Big Data or Healthcare sessions. The interesting thing is that the Big Data sessions always devolved to ta...
Category: Strategy
Repeated evolution in sticklebacks, and adjacent possibles
“Researchers have documented repeated evolution in other organisms, but the sticklebacks are unique because the freshwater transition has occurred so many...
The wacky world of horizontal gene transfer, genomic variants, and what we think are microbial species
“The main difference from eukaryotes is that prokaryotic reproduction is independent of DNA acquisition and recombination. Instead, DNA is obtained from f...
Another article on “Patterns of Early Gut Colonization Shape Future Immune Responses of the Host” in PLoS ONE
“In conclusion, a time window exists that enables the artificial colonization of GF mice by a single oral dose of caecal content, which may modify the fut...
New Old Publishing and “The New Value of Text”
“Finally, the text still requires context. As publishers spin up their digital and print-on-demand backlists, more and more is published with less and les...
Gut microbes and immunity: The hygiene hypothesis, peak antibiotics, and the post-Pasteurian Age
“Exposure to microbes during early childhood is associated with protection from immune-mediated diseases such as inflammatory bowel disease (IBD) and asth...
A Method for Generation Phage Cocktail with Great Therapeutic Potential – PLoS ONE
“Bacteriophage could be an alternative to conventional antibiotic therapy against multidrug-resistant bacteria. However, the emergence of resistant varian...
Broad Institute Gets $32.5 Million to Map Cell Circuits – ScienceInsider
“The Broad isn’t alone: Mount Sinai School of Medicine in New York City, the Allen Institute for Brain Science in Seattle, the Salk Institute in San...
Two-Drug Antimicrobial Chemotherapy: A Mathematical Model and Experiments with Mycobacterium marinum – PLoS Pathogens
This paper is trying to measure and model the effectiveness of multi-drug antimicrobial chemotherapy. Antibiotics are notorious for losing effectiveness as the ...
Patterns of Gene Flow Define Species of Thermophilic Archaea: PLoS Biology
“Patterns of homologous gene flow among genomes of 12 strains from a single hot spring in Kamchatka, Russia, demonstrate higher levels of gene flow within...